This data set describes antimicrobial resistance (AMR) data from the WHO European Region gathered through the Central Asian and Eastern European Surveillance of Antimicrobial Resistance (CAESAR) network and the European Centre for Disease Prevention and Control (ECDC) European Antimicrobial Resistance Surveillance Network (EARS-Net). The data set aims to create awareness about antibiotic resistance situation and advocate AMR control policies in participating countries. Data is available for 19 countries and Kosovo (in accordance with United Nations Security Council resolution 1244 (1999)) within CAESAR, and 30 countries within EARS-Net; with remaining WHO European Region Member States marked as “Did not participate in survey” in the dataset.